Maca Root

This peruvian root, long used by spanish royalty, helps improve memory recall ability and overall learning ability. This super root is also known for its ability to protect against depression and age-related cognitive decline.

 

References: 

Rubio, J., Caldas, M., Dávila, S., Gasco, M., & Gonzales, G. F. (2006). Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice. BMC Complementary and Alternative Medicine,6(1). doi:10.1186/1472-6882-6-23

Conclusion: “Black Maca appeared to have more beneficial effects on latent learning in OVX mice; meanwhile, all varieties of Maca showed antidepressant activity.”

Rubio, J., Dang, H., Gong, M., Liu, X., Chen, S., & Gonzales, G. F. (2007). Aqueous and hydroalcoholic extracts of Black Maca (Lepidium meyenii) improve scopolamine-induced memory impairment in mice. Food and Chemical Toxicology,45(10), 1882-1890. doi:10.1016/j.fct.2007.04.002

Conclusion: Both extracts of Black Maca significantly ameliorated the scopolamine-induced memory impairment as measured in both the water Morris maze and the step-down avoidance tests. Black Maca extracts inhibited AChE activity, whereas MAO activity was not affected. These results indicate that Black Maca improves scopolamine-induced memory deficits.”

Pino-Figueroa, A., Nguyen, D., & Maher, T. J. (2010). Neuroprotective effects of Lepidium meyenii (Maca). Annals of the New York Academy of Sciences,1199(1), 77-85. doi:10.1111/j.1749-6632.2009.05174.x

Guo, S., Gao, X., Gu, Y., Wan, Z., Lu, A., Qin, Z., & Luo, L. (2016). Preservation of Cognitive Function by Lepidium meyenii(Maca) Is Associated with Improvement of Mitochondrial Activity and Upregulation of Autophagy-Related Proteins in Middle-Aged Mouse Cortex. Evidence-Based Complementary and Alternative Medicine,2016, 1-9. doi:10.1155/2016/4394261

Conclusion: “ Our findings suggest that maca is a newly defined nutritional plant which can improve mitochondrial function and upregulate autophagy-related proteins and may be an effective functional food for slowing down age-related cognitive decline.”




Also in The Clean Library

Eleuthero Root

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Also known as Siberian Ginseng, this adaptogen is the “king” of them all. There are more published studies on Eleuthero Root than any other herb (wow!). This superherb decreases fatigue by increasing your work and exercise capacity without the “crash” that comes with a morning cup of coffee. With this herb, you’ll also recover faster from acute stress and intense workouts. Check out the research for more interesting tidbits on what Eleuthero can do.
Reishi Mushroom

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Reishi is an ethereal yellow-red mushroom that has been used as a medicine for over two thousand years. It both regulates and restores the body to homeostasis as well as relieves one from stress.
Turmeric

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This bright yellow root has been used in both Indian and Chinese traditional medicine for centuries. Curcumin, the active chemical compound in turmeric, has anti-inflammatory properties that can reduce depression and pain. Studies have shown that oral intake of curcumin helps with acne, atopic dermatitis, and facial photoaging (sun damage). In this formulation, turmeric is paired with black pepper in order to increase the bioavailability of curcumin.

 

Further Reading

Thangapazham, R. L., Sharma, A., & Maheshwari, R. K. (n.d.). Beneficial Role Of Curcumin In Skin Diseases. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease, 343-357. doi:10.1007/978-0-387-46401-5_15

 

Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243-1264. doi:10.1002/ptr.5640

 

Disilvestro, R. A., Joseph, E., Zhao, S., & Bomser, J. (2012). Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutrition Journal, 11(1). doi:10.1186/1475-2891-11-79

 

Kalpravidh, R. W., Siritanaratkul, N., Insain, P., Charoensakdi, R., Panichkul, N., Hatairaktham, S., . . . Fucharoen, S. (2010). Improvement in oxidative stress and antioxidant parameters in β-thalassemia/Hb E patients treated with curcuminoids. Clinical Biochemistry, 43(4-5), 424-429. doi:10.1016/j.clinbiochem.2009.10.057

 

Al-Jassabi, S., Ahmed, K., & Abdulla, M. (2012). Antioxidant Effect of Curcumin Against Microcystin- LR-Induced Renal Oxidative Damage in Balb/c Mice. Tropical Journal of Pharmaceutical Research, 11(4). doi:10.4314/tjpr.v11i4.2

 

Biswas, J., Sinha, D., Mukherjee, S., Roy, S., Siddiqi, M., & Roy, M. (2010). Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal. Human & Experimental Toxicology, 29(6), 513-524. doi:10.1177/0960327109359020

 

Chainani-Wu, N., Madden, E., Lozada-Nur, F., & Silverman, S. (2012). High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. Journal of the American Academy of Dermatology, 66(5), 752-760. doi:10.1016/j.jaad.2011.04.022

 

Khajehdehi, P., Pakfetrat, M., Javidnia, K., Azad, F., Malekmakan, L., Nasab, M. H., & Dehghanzadeh, G. (2011). Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: A randomized, double-blind and placebo-controlled study. Scandinavian Journal of Urology and Nephrology, 45(5), 365-370. doi:10.3109/00365599.2011.585622

 

Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., & Dehghanzadeh, G. (2012). Oral Supplementation of Turmeric Decreases Proteinuria, Hematuria, and Systolic Blood Pressure in Patients Suffering From Relapsing or Refractory Lupus Nephritis: A Randomized and Placebo-controlled Study. Journal of Renal Nutrition, 22(1), 50-57. doi:10.1053/j.jrn.2011.03.002

 

Disilvestro, R. A., Joseph, E., Zhao, S., & Bomser, J. (2012). Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutrition Journal, 11(1). doi:10.1186/1475-2891-11-79

 

Kalpravidh, R. W., Siritanaratkul, N., Insain, P., Charoensakdi, R., Panichkul, N., Hatairaktham, S., . . . Fucharoen, S. (2010). Improvement in oxidative stress and antioxidant parameters in β-thalassemia/Hb E patients treated with curcuminoids. Clinical Biochemistry, 43(4-5), 424-429. doi:10.1016/j.clinbiochem.2009.10.057


Pungcharoenkul, K., & Thongnopnua, P. (2011). Effect of Different Curcuminoid Supplement Dosages on TotalIn VivoAntioxidant Capacity and Cholesterol Levels of Healthy Human Subjects. Phytotherapy Research, 25(11), 1721-1726. doi:10.1002/ptr.3608